CWIS NON-FLAIL Clinical Trial
A multicenter, prospective, controlled clinical trial of surgical stabilization of rib fractures in patients with severe, non-flail fracture pattern
Principal investigator:
Fredric M. Pieracci, MD, MPH, FACS
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Identifiers:
CWIS Study ID: CWIS NON-FLAIL
NCT trial no. 03221595
COMIRB study ID: 17-1432
JTACS MS no. JT-D-10-10019R2
DPS grant ID: DPS-TCMF-2017-016
PMID 31804414
Hypothesis: SSRF, as compared to standardized non-operative management, improves pain control, pulmonary function, risk of complications, and quality of life among patients with severe, non-flail chest fracture patterns
UPDATE: THIS TRIAL COMPLETED ENROLLMENT IN JUNE 2019, AND HAS BEEN ACCEPTED FOR PUBLICATION IN THE JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. LINK: https://www.ncbi.nlm.nih.gov/
The objective of this trial was to investigate the efficacy of surgical stabilization of rib fractures (SSRF), as compared to non-operative management, for hospitalized patients with non-flail, severe rib fractures.
The study was conducted within 12 expert, high-volume centers that participate in the Chest Wall Injury Society (CWIS).
The trial was sponsored in part by an investigator-initiated research grant from DePuy Synthes, Inc.
Full slide deck available
These standard trial slides include methods and results - and are exclusive for CWIS members. They cannot be modified from their original form.
Participating Site PIs
Fredric M. Pieracci, MD, MPH
Denver Health Medical Center, Denver CO
Fredric.pieracci@dhha.org
Kiara Leasia, MD
Denver Health Medical Center, Denver CO
Kiara.Leasia@dhha.org
Zach Bauman, DO
Univ. of Nebraska Medical Center, Omaha, NE
Zachary.bauman@unmc.edu
Evert A. Eriksson, MD
Medical Univ. of South Carolina, Charleston, SC
Evert.eriksson@gmail.com
Lawrence Lottenberg, MD
St. Mary's Medical Center, West Palm Beach, FL
Larwence.lottenberg@gmail.com
Sarah Majercik, MD
Intermountain Medical Center, Murray, UT
Sarah.majercik@imail.org
Ledford Powell, MD
St. Joseph Health, Mission Viejo, CA
Ledford.powell@gmail.com
Babak Sarani, MD
George Washington University, Washington, DC
bsarani@mfa.gwu.edu
Gregory Semon, DO
Wright State University/Miami Valley Hospital
gsemon@premierhealth.com
Bradley Thomas, MD
Carolinas Medical Center, Charlotte, NC
Bradley.thomas@carolinashealthcare.org
Frank Zhao, MD
The Queens Medical Center, Honolulu, HI
Frank.z.zhao@gmail.com
Cornelius Dyke, MD
Sanford Health, Fargo, ND
Cornelius.dyke@sanfordhealth.org
Andrew R. Doben, MD
Baystate Medical Center, Springfield, MA
andy@dobenonline.com